Bioshock 2 Walkthrough Persephone

September 12, 2016 (Last Updated: ) | Reading Time: 3 minutes

This Bioshock 2 walkthrough is divided into 10 total pages.

You can jump to nearby pages of the game using the links above.

Persephone

Bioshock 2 Walkthrough - Bioshock 2 295
Bioshock 2 Walkthrough - Bioshock 2 295

An upgrade station will be near the entrance.

Bioshock 2 Walkthrough - Bioshock 2 296
Bioshock 2 Walkthrough - Bioshock 2 296

Follow the sign to the quarantine area.

Bioshock 2 Walkthrough - Bioshock 2 297
Bioshock 2 Walkthrough - Bioshock 2 297

Enter the control room.

Bioshock 2 Walkthrough - Bioshock 2 298
Bioshock 2 Walkthrough - Bioshock 2 298

Go near the red quarantine area room.

Bioshock 2 Walkthrough - Bioshock 2 299
Bioshock 2 Walkthrough - Bioshock 2 299

Activate the controls.

Bioshock 2 Walkthrough - Bioshock 2 300
Bioshock 2 Walkthrough - Bioshock 2 300

Fight the two big sisters that will attack you.

Bioshock 2 Walkthrough - Bioshock 2 301
Bioshock 2 Walkthrough - Bioshock 2 301

Get inside the quarantine chamber.

Bioshock 2 Walkthrough - Bioshock 2 302
Bioshock 2 Walkthrough - Bioshock 2 302

Lamb will try to kill Eleanor. The cutscene will show you how you take control of a little sister.

Bioshock 2 Walkthrough - Bioshock 2 303
Bioshock 2 Walkthrough - Bioshock 2 303

You will play as a little sister for now. Enter the vent.

Bioshock 2 Walkthrough - Bioshock 2 304
Bioshock 2 Walkthrough - Bioshock 2 304

The world will look different through the eyes of the little sister.

Bioshock 2 Walkthrough - Bioshock 2 305
Bioshock 2 Walkthrough - Bioshock 2 305

Enter the next vent.

Bioshock 2 Walkthrough - Bioshock 2 306
Bioshock 2 Walkthrough - Bioshock 2 306

Go through the corridor with a large bookcase.

Bioshock 2 Walkthrough - Bioshock 2 307
Bioshock 2 Walkthrough - Bioshock 2 307

Use the lever.

Bioshock 2 Walkthrough - Bioshock 2 308
Bioshock 2 Walkthrough - Bioshock 2 308

Go up the stairs.

Bioshock 2 Walkthrough - Bioshock 2 309
Bioshock 2 Walkthrough - Bioshock 2 309

Go left from here.

Bioshock 2 Walkthrough - Bioshock 2 310
Bioshock 2 Walkthrough - Bioshock 2 310

Enter the room that has flowers.

Bioshock 2 Walkthrough - Bioshock 2 311
Bioshock 2 Walkthrough - Bioshock 2 311

You can gather some ADAM from the corpse.

Bioshock 2 Walkthrough - Bioshock 2 312
Bioshock 2 Walkthrough - Bioshock 2 312

Up the stairs with flowers.

Bioshock 2 Walkthrough - Bioshock 2 313
Bioshock 2 Walkthrough - Bioshock 2 313

Approach the dress and pick it up. It's one of the pieces of the big sister suit you need.

Bioshock 2 Walkthrough - Bioshock 2 314
Bioshock 2 Walkthrough - Bioshock 2 314

The people won't attack you if you don't go near them.

Bioshock 2 Walkthrough - Bioshock 2 315
Bioshock 2 Walkthrough - Bioshock 2 315

Approach the big statue here.

Bioshock 2 Walkthrough - Bioshock 2 316
Bioshock 2 Walkthrough - Bioshock 2 316

Pick up the big sister helmet.

Bioshock 2 Walkthrough - Bioshock 2 317
Bioshock 2 Walkthrough - Bioshock 2 317

Go up the stairs.

Bioshock 2 Walkthrough - Bioshock 2 318
Bioshock 2 Walkthrough - Bioshock 2 318

Avoid these guys and go around.

Bioshock 2 Walkthrough - Bioshock 2 319
Bioshock 2 Walkthrough - Bioshock 2 319

You can gather some more ADAM.

Bioshock 2 Walkthrough - Bioshock 2 320
Bioshock 2 Walkthrough - Bioshock 2 320

Pick up the big sister gloves from here.

Bioshock 2 Walkthrough - Bioshock 2 321
Bioshock 2 Walkthrough - Bioshock 2 321

Exit through this gate.

Bioshock 2 Walkthrough - Bioshock 2 322
Bioshock 2 Walkthrough - Bioshock 2 322

Backtrack through here.

Bioshock 2 Walkthrough - Bioshock 2 323
Bioshock 2 Walkthrough - Bioshock 2 323

Enter the office of Lamb.

Bioshock 2 Walkthrough - Bioshock 2 324
Bioshock 2 Walkthrough - Bioshock 2 324

Approach Eleanor.

Bioshock 2 Walkthrough - Bioshock 2 325
Bioshock 2 Walkthrough - Bioshock 2 325

Give the big sister suit to Eleanor.

Bioshock 2 Walkthrough - Bioshock 2 326
Bioshock 2 Walkthrough - Bioshock 2 326

Eleanor will put on the suit. She will save the little sister just like you did if you have saved them before.

Bioshock 2 Walkthrough - Bioshock 2 327
Bioshock 2 Walkthrough - Bioshock 2 327

She will give you a plasmid to summon her whenever you are in a tight spot.

Bioshock 2 Walkthrough - Bioshock 2 328
Bioshock 2 Walkthrough - Bioshock 2 328

Dr. Lamb will tell you that she will blow up some bombs and bury you underwater.

Bioshock 2 Walkthrough - Bioshock 2 329
Bioshock 2 Walkthrough - Bioshock 2 329

Go inside the facility.

Bioshock 2 Walkthrough - Bioshock 2 330
Bioshock 2 Walkthrough - Bioshock 2 330

Use the door to travel to the next level.

More Bioshock 2 Walkthroughs

This Bioshock 2 walkthrough is divided into 10 total pages.

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