This Bioshock 2 walkthrough is divided into 10 total pages.
You can jump to nearby pages of the game using the links above.
Persephone
![Bioshock 2 Walkthrough - Bioshock 2 295](bioshock-2-295-small.webp)
An upgrade station will be near the entrance.
![Bioshock 2 Walkthrough - Bioshock 2 296](bioshock-2-296-small.webp)
Follow the sign to the quarantine area.
![Bioshock 2 Walkthrough - Bioshock 2 297](bioshock-2-297-small.webp)
Enter the control room.
![Bioshock 2 Walkthrough - Bioshock 2 298](bioshock-2-298-small.webp)
Go near the red quarantine area room.
![Bioshock 2 Walkthrough - Bioshock 2 299](bioshock-2-299-small.webp)
Activate the controls.
![Bioshock 2 Walkthrough - Bioshock 2 300](bioshock-2-300-small.webp)
Fight the two big sisters that will attack you.
![Bioshock 2 Walkthrough - Bioshock 2 301](bioshock-2-301-small.webp)
Get inside the quarantine chamber.
![Bioshock 2 Walkthrough - Bioshock 2 302](bioshock-2-302-small.webp)
Lamb will try to kill Eleanor. The cutscene will show you how you take control of a little sister.
![Bioshock 2 Walkthrough - Bioshock 2 303](bioshock-2-303-small.webp)
You will play as a little sister for now. Enter the vent.
![Bioshock 2 Walkthrough - Bioshock 2 304](bioshock-2-304-small.webp)
The world will look different through the eyes of the little sister.
![Bioshock 2 Walkthrough - Bioshock 2 305](bioshock-2-305-small.webp)
Enter the next vent.
![Bioshock 2 Walkthrough - Bioshock 2 306](bioshock-2-306-small.webp)
Go through the corridor with a large bookcase.
![Bioshock 2 Walkthrough - Bioshock 2 307](bioshock-2-307-small.webp)
Use the lever.
![Bioshock 2 Walkthrough - Bioshock 2 308](bioshock-2-308-small.webp)
Go up the stairs.
![Bioshock 2 Walkthrough - Bioshock 2 309](bioshock-2-309-small.webp)
Go left from here.
![Bioshock 2 Walkthrough - Bioshock 2 310](bioshock-2-310-small.webp)
Enter the room that has flowers.
![Bioshock 2 Walkthrough - Bioshock 2 311](bioshock-2-311-small.webp)
You can gather some ADAM from the corpse.
![Bioshock 2 Walkthrough - Bioshock 2 312](bioshock-2-312-small.webp)
Up the stairs with flowers.
![Bioshock 2 Walkthrough - Bioshock 2 313](bioshock-2-313-small.webp)
Approach the dress and pick it up. It's one of the pieces of the big sister suit you need.
![Bioshock 2 Walkthrough - Bioshock 2 314](bioshock-2-314-small.webp)
The people won't attack you if you don't go near them.
![Bioshock 2 Walkthrough - Bioshock 2 315](bioshock-2-315-small.webp)
Approach the big statue here.
![Bioshock 2 Walkthrough - Bioshock 2 316](bioshock-2-316-small.webp)
Pick up the big sister helmet.
![Bioshock 2 Walkthrough - Bioshock 2 317](bioshock-2-317-small.webp)
Go up the stairs.
![Bioshock 2 Walkthrough - Bioshock 2 318](bioshock-2-318-small.webp)
Avoid these guys and go around.
![Bioshock 2 Walkthrough - Bioshock 2 319](bioshock-2-319-small.webp)
You can gather some more ADAM.
![Bioshock 2 Walkthrough - Bioshock 2 320](bioshock-2-320-small.webp)
Pick up the big sister gloves from here.
![Bioshock 2 Walkthrough - Bioshock 2 321](bioshock-2-321-small.webp)
Exit through this gate.
![Bioshock 2 Walkthrough - Bioshock 2 322](bioshock-2-322-small.webp)
Backtrack through here.
![Bioshock 2 Walkthrough - Bioshock 2 323](bioshock-2-323-small.webp)
Enter the office of Lamb.
![Bioshock 2 Walkthrough - Bioshock 2 324](bioshock-2-324-small.webp)
Approach Eleanor.
![Bioshock 2 Walkthrough - Bioshock 2 325](bioshock-2-325-small.webp)
Give the big sister suit to Eleanor.
![Bioshock 2 Walkthrough - Bioshock 2 326](bioshock-2-326-small.webp)
Eleanor will put on the suit. She will save the little sister just like you did if you have saved them before.
![Bioshock 2 Walkthrough - Bioshock 2 327](bioshock-2-327-small.webp)
She will give you a plasmid to summon her whenever you are in a tight spot.
![Bioshock 2 Walkthrough - Bioshock 2 328](bioshock-2-328-small.webp)
Dr. Lamb will tell you that she will blow up some bombs and bury you underwater.
![Bioshock 2 Walkthrough - Bioshock 2 329](bioshock-2-329-small.webp)
Go inside the facility.
![Bioshock 2 Walkthrough - Bioshock 2 330](bioshock-2-330-small.webp)
Use the door to travel to the next level.
More Bioshock 2 Walkthroughs
This Bioshock 2 walkthrough is divided into 10 total pages.